職務名稱：Postdoctoral Research Scientist
系所/單位名稱：Dr Zoi Diamantopoulou
申請人資格：
About us
The CRUK Scotland Institute where the lab is based is a world leading cancer research institute, situated in the vibrant city of Glasgow in Scotland and hosting approximately 60 postdoctoral researcher scientists at any one time. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned for in vivo modelling of tumour growth and metastasis.
Project outline
We are seeking an enthusiastic Postdoctoral Research Scientist with a strong passion for unravelling the complexities of metastasis to work on an ambitious project fully funded by the UKRI Future Leaders Fellowship. The project is to investigate the intricate relationship between metastasis and the circadian rhythm. Our research builds upon our recent publication, which demonstrates that breast cancer cells spread during sleep (https://www.nature.com/articles/s41586-022-04875-y).
The successful candidate will analyse a range of breast cancer mouse models available at the CRUK Scotland Institute and cancer patient samples to uncover the mechanisms through which the circadian rhythm regulates the metastatic spread of Circulating Tumour Cells (CTCs) and identify molecular targets for therapeutic intervention. This will involve a combination of cutting-edge microfluidics and robotic technologies, along with spatial transcriptomics, single-cell analysis methods, next generation sequencing, CRISPR screens and imaging techniques.
To be considered for this position you will have successfully (or nearly) completed a PhD in a relevant field. Expertise in working with mouse models is essential and proficiency in R or Python for omic data analysis is desirable. While prior research experience with CTCs or circadian rhythm would be advantageous, it is not mandatory, as appropriate training will be provided. Finally, you should also demonstrate the ability to conduct both independent and collaborative research and have strong planning and prioritisation skills to ensure project timelines are met.
聘期：Fixed up to 6 years, subject to successful review at Year 3.
薪資待遇：from £37,000 to £44,852 subject to experience, plus relocation allowance and visa costs if required.
受理期間：2025年11月7日止 (we may contact promising candidates on a rolling basis, so please apply as soon as you are ready.)
相關細節請參考網址：https://www.crukscotlandinstitute.ac.uk/careers/postdoctoral-fellows/2105-postdoc-zd-nov25.html
