職務名稱：Postdoctoral Scientist
系所/單位名稱：Systems Oncology Group
申請人資格：
About the role
Dr Claus Jorgensen, Group Leader of the Systems Oncology Group, is looking for a Postdoctoral Scientist to join his group. This is a great opportunity for a self-motivated, innovative, meticulous and organised candidate who is keen to work in a dynamic laboratory undertaking cutting edge research. The goal of the Systems Oncology Group is to understand how the tumour microenvironment, and the desmoplastic reaction, regulates tumour cell function and therapeutic response in pancreatic ductal adenocarcinoma.
Specifically, the post holder will use a number of in vitro cell biology assays to assess cell function and biochemical assays to assess cell signalling in vitro; this will include functional CRISPR screening and mass spectrometry analysis in 2D and 3D cell models. Tumour models will be analysed by IF/IHC, proteomics, genomics and transcriptionally as well as testing novel combination treatments using available in vivo models (see Hutton et al Cancer Cell 2021, Lee et al Nat Comm 2021 and Below et al Nat Mat 2022). This is a project for a highly collaborative individual seeking to make a difference in a very hard to treat cancer.
About you
You should have a PhD in biochemistry, cancer biology, cell biology, immunology or a related field. Experience in protein biochemistry, analysis of cell signalling and use of in vitro models of cancer is required. Experience with in vivo tumour models and immunology is desirable. Key qualities include independent thinking, ability to work in a team and good communication skills, all of which are needed to efficiently work in a multidisciplinary team.
聘期：Fixed term until 28th February 2027
薪資待遇：£37,000 – £44,852 (depending on qualifications and experience)
受理期間：2025年7月6日止 (We reserve the right to close this vacancy early before the closing date if enough applications are received.)
相關細節請參考網址：https://www.cruk.manchester.ac.uk/career/mi-25-33-postdoctoral-scientist-systems-oncology-group/
