工作內容：
The major research interests in the LAI lab are to understand the molecular mechanisms underlying how bacterial pathogens deploy protein secretion systems for survival at its ecological niche and successful infection inside the plant host. We study the mechanistic and biological insights of the two major protein secretion nanomachines, type IV and type VI secretion systems (T4SS and T6SS), in Agrobacterium tumefaciens, the causal agent of crown gall disease and powerful gene transfer tool. We also aim to identify novel agrobacterial and plant genes critical for plant transformation and gene editing. The knowledge may provide new insights to improve Agrobacterium-mediated plant transformation and translational applications in biomedicine and/or agriculture.
The postdoc will carry out a two-year research grant to study the antibacterial T6SS with focuses to investigate the T6SS evolution and assembly mechanisms.
The LAI lab provides the research environments and expertise on studies of protein secretion and pathogen-plant interactions using various tools including genetics/genomics, molecular biology, biochemistry/proteomics, and cell biology. The research may expand to study structural aspects of T6SS-assocaited protein complex using X-ray crystallography and cryoEM. The postdoc is also encouraged to develop an independent project and will be trained to serve as a mentor toward an independent investigator. The LAI lab is also active in international collaborations, which will bring opportunities for abroad training.
應徵資格：
對微生物學研究具有高度熱忱，並至少具備下列兩項專長或研究經驗者：細菌遺傳學、蛋白質化學、電子顯微鏡技術或生物資訊分析。
工作待遇: NT$64711起，依據經驗、專長及規定支薪
應備文件：請以電子郵件方式寄履歷及相關文件(含兩位推薦者聯絡方式)到賴爾珉博士信箱 (emlai@gate.sinica.edu.tw)。合適者將通知面談。
聯絡人：賴爾珉
聯絡電話：02-27871158 or 02-27871031
電子信箱：emlai@gate.sinica.edu.tw
發佈日期：2026-08-05 00:00:00
