職務名稱：Postdoctoral Research Scientist
系所/單位名稱：Research Faculty Department
申請人資格：
The recently funded Horizon NextGen consortium encompassing 21 organisations across Europe aiming at developing federated approaches to enable the integration of multimodal and multiomic resources for applications in the areas of cardiovascular medicine. As part of this highly collaborative project bringing together computer scientists, data scientists, bioinformaticians, clinicians across academia and industry, we are seeking an enthusiastic and ambitious Postdoctoral Research Scientist to undertake computational analysis of the functional implications of variation within noncoding functional sequences in relation to cardiovascular disorders.
The role
The post holder will lead on the development and testing to applications to identify noncoding functional elements based on integration of multi-omic data (genome, transcriptome, epigenome) and integrate this novel information in the development of tissue / condition specific regulatory network, with the aim of prioritising variants occurring within those regions based on their predicted impact. They will also lead on the analysis, preparation, and submission of the associated manuscripts. The successful candidate will develop computational pipelines centred on machine learning applications such as convolutional neural network to reproducibly handle multi-omic data (genome, transcriptome, epigenome) to enable functional sequence annotation, network reconstruction, and the interpretation of the implication of genetic variation within those disorders.
The ideal candidate
The successful applicant will have a PhD in bioinformatics, computational genomics or a related subject. They will have significant experience working with genomic/epigenomic/transcriptomic data, and experience with machine learning applications in genomics investigations. The candidate should have a demonstrable working knowledge of programming languages such as Python, Perl, or R.
聘期：This is a full-time post until 31 December 2027, with a possibility of a 6-month extension.
薪資待遇：Salary on appointment will be within the range £36,720 to £39,750 per annum depending on qualifications and experience.
受理期間：2025年6月9日止 (We reserve the right to close this vacancy early before the closing date if enough applications are received.)
相關細節請參考網址：https://www.earlham.ac.uk/vacancy/postdoctoral-research-scientist-nextgen
